NMA: Nonprescription Medicines Academy

New Review Addresses Use of Herbal Products, Potential Interactions in Patients With Cardiovascular Disease

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February 22nd, 2010

Possible cardiovascular adverse effects of common herbal remedies—including interactions with cardiovascular drugs—are addressed in a “State-of-the-Art Paper” in the February 9, 2010, issue of Journal of the American College of Cardiology.

Among the herbal remedies discussed in the paper are St. John's wort, motherwort, ginseng, gingko biloba, garlic, grapefruit juice, hawthorn, saw palmetto, danshen, echinacea, tetrandrine, aconite, yohimbine, gynura, licorice, and black cohosh. Tables highlight products that can potentiate the risk of bleeding or arrhythmogenesis, as well as products that may interfere with digoxin levels and assays.

The article concludes with recommendations for improving the safety of herbal products.
J Am Coll Cardiol. 2010;55:515-25.